
Yes, patients find PRP injection uncomfortable, depending on the site of injection or the patient’s threshold for pain. In fact, many often ask if platelet rich plasma injections hurt. Most descriptions of discomfort describe mild pain—soreness is frequently mentioned—with a risk of bruises. Some patients have reported feelings of tingling or burning during the injection that fade very quickly.
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What Is PRP Injection (Platelet-Rich Plasma Injection)?
PRP injections consist of a preparation of platelet-rich plasma derived from the blood of the patient. The platelets are components of blood that contain proteins, called growth factors, that aid healing. The liquid component of the blood is called plasma. In preparing PRP, the healthcare provider spins a sample of the blood in a machine. Following the procedure, blood is drawn, the cells are separated, and are added back into the plasma to concentrate the platelets.
Injection of PRP (platelet-rich plasma) contains five to ten times more platelets than a sample of normal blood. The providers administer PRP injections into the injured or diseased tissues so that the growth factors in the platelets may accelerate improvement of one’s symptoms. Some patients may wonder whether platelet rich plasma injections hurt, but the procedure is generally well-tolerated and frequently promotes wound healing after injury. Applications for PRP injections in pain relief include osteoarthritis, but also have potential dermatologic and hair loss applications.
Treatment Details During the Procedure
It’s commonly accepted that mild discomfort would be experienced during the injection, as in any other case. Possibly, a local anesthetic might have been used to lessen the pain.
- Discomfort: Mild soreness, tenderness, or stiffness at the injection site may last for no longer than 48 hours after the procedure.
- Bruising: Bruising would also likely occur.
- Tingling or burning: Some patients have experienced a short-lived burning or tingling sensation after injection, lasting a few minutes before fading away.
Criteria governing the utility or ability to rate discomfort:
- Location: The site of injury and the area where the injection is made may determine the degree of pain.
- Personal tolerance: Pain perception varies from patient to patient.
- Type of PRP: Whether white blood cells are combined with the PRP or not would also determine the level of inflammation and discomfort experienced.
Will I Have To Prepare for PRP Treatment if Platelet Rich Plasma Injections Hurt?
Your healthcare provider may ask you to cease taking specific medications, such as blood thinners or NSAIDs, before your PRP injection. They will also want to go over your medical history to ensure that the treatment is suitable for you. Some patients may worry that platelet rich plasma injections hurt, but discomfort is generally mild and temporary. If you have certain blood conditions, you may not qualify for PRP injections.
What Exactly Happens in Platelet-Rich Plasma Procedures?
The practice may change depending on the specific therapy, yet it will widely maintain similar processes and protocols.
The provider will take blood from you and analyze it for some sort of platelet-rich plasma. Working off your own blood avoids complications connected with donor blood, and blood analysis may require one or multiple vials collected. Put your sample in a centrifuge. Spinning your blood separates the weight of the components. From this, blood cells will eventually be removed and platelets concentrated.
Now take the finished product and inject it into your tissues. Your provider may use an ultrasound to find the right spot. Anesthesia may be given before or along with the PRP injection.

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How Long Does a PRP Injection Take?
Therapeutic PRP, injected into an affected joint or injury, lasts about 60 minutes from start to finish. Cosmetically, the PRP facelift or PRP for lost hair may take longer, as there may be additional steps. Your health care provider will advise you on what to expect.
What Are the Advantages of the Platelet-Rich Plasma Injection?
Research studies suggest that PRP injection may stimulate healing in tissues that have been slow to heal or have resistant healing properties.
Probably, they do it by:
- Causing inflammation of your tissues on a short-term basis, which initiates the healing process.
- Stimulating collagen production, your body needs this important protein to build tissue.
- Promoting the division and turnover of cells, both activities that are slowed by aging and disease.
- They reduce inflammation, which is usually what chronically hurts, because you have been suffering from it for a long time.
What Risks Do PRP Injections Entail?
PRP injection is extremely safe and poses rare risks; however, if an establishment fails to maintain a sterile environment while handling your blood, contamination remains a possibility. Clinics have robust sanitization protocols to prevent any occurrence of such incidents, but some patients still wonder if platelet rich plasma injections hurt, as there remains a possibility that the injection is more discomforting than initially expected.
The preparation of platelet-rich plasma is resource-intensive and thus quite costly. Another production-limiting factor is that, being an autologous product, PRP cannot be mass-produced. Having said that, if you are dealing with a chronic condition, you may weigh this against the benefits received vs. the cost for multiple applications.
What To Expect After My PRP Injection?
PRP treatment usually results in swelling and pain for the first few days, as it stimulates the healing process as though an injury had occurred. While some patients wonder if platelet rich plasma injections hurt, the inflammation that follows is actually a positive sign, as it creates swelling and pain that suggest the beginning of healing. Symptoms may last for a day or two after the treatment.
How Long After PRP Treatment do Effects Begin To Show?
Two weeks might be necessary to show or feel the first effects of pain relief or perhaps cosmetic improvement, with several months being required for any complete recovery of injured or affected tissue or any new hair growth. Some may require multiple PRP treatments to meet their expected results.
How Long Does the Effect of PRP Treatment Last?
The period after which the effects of a PRP injection will last ranges from 6 months to over a year, depending on the condition involved. Symptoms would likely improve progressively during this time. In addition to temporarily relieving pain, platelet-rich plasma will improve the general state over time.

Bottom Line!
PRP treatment at Dvida Medical Spa is simply learning the healing way. Chronic pain relief, injury repair, skin rejuvenation, and hair rejuvenation? Our professionals assure that PRP treatment is the best, most efficient, and most secure form of therapy for the patient. Some patients may wonder if platelet rich plasma injections hurt, but our team ensures maximum comfort with expert care and modern techniques. Alleviate pain and slow recovery, but use advanced regenerative medicine for fast healing.
Call us now to schedule an appointment for PRP treatment at Dvida Med Spa, the first step toward simple healing and regaining confidence!
In a Hurry? Dial 312-374-3352 now!